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All South America Cruises

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341 Cruises (1,746 Cruise Departures)
14 Day Galapagos Voyager: Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

14 Days (13 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 4,654
From 10,685
View Trip
9 Day Galapagos - Central & West Islands aboard the Treasure with Explore!
Cruise

9 Days (8 Nights) Quito to Quito
Operated By: Explore!
Departures: May 2024 to Dec 2024
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 276
From 12,152
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8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 March 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,485
OCEANVIEW
$1,654
BALCONY
$1,891
SUITE
$3,089
From 1,485
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departures: Dec 2024 to Jan 2025
Countries Visited: Brazil, Uruguay, Argentina
Early Booking Offer
INSIDE
$1,277
OCEANVIEW
$1,456
BALCONY
$2,109
SUITE
$2,515
From 1,277
View Trip
10 Day Classic Galapagos: Central Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,115
From 7,389
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) São Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Nov 2024 to Mar 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$916
OCEANVIEW
$1,045
BALCONY
$1,194
SUITE
$1,540
From 916
View Trip
6 Day South America with MSC Cruises
Cruise

6 Days (5 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 24 December 2024
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,373
OCEANVIEW
$1,462
BALCONY
$1,660
SUITE
$3,947
From 1,373
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 10 March 2025
Countries Visited: Uruguay, Brazil, Argentina
Early Booking Offer
INSIDE
$1,983
OCEANVIEW
$2,241
BALCONY
$2,686
SUITE
-
From 1,983
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 08 February 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,188
OCEANVIEW
$1,376
BALCONY
$1,614
SUITE
$2,812
From 1,188
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departure: 21 March 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$37,323
From 20,592
View Trip
10 Day Classic Galapagos: South Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,114
From 7,206
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15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Oct 2024 to Nov 2025
Countries Visited: Chile, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$11,206
BALCONY
$12,000
SUITE
$19,438
Save 275
From 11,206
View Trip
12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Jul 2024 to Nov 2024
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
Exclusive Solo Offer
From 26,490
View Trip
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
From 15,361
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Jun 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 165
From 9,934
View Trip
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Sep 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Mothers Day Sale
Save 197
From 9,871
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Maceio to Maceio
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,307
OCEANVIEW
$1,485
BALCONY
$1,733
SUITE
$3,248
From 1,307
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 01 March 2025
Countries Visited: Uruguay, Brazil, Argentina
Early Booking Offer
INSIDE
$1,983
OCEANVIEW
$2,241
BALCONY
$2,686
SUITE
-
From 1,983
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Paranagua to Paranagua
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departures: Dec 2024 to Jan 2025
Countries Visited: Brazil, Uruguay, Argentina
Early Booking Offer
INSIDE
$1,297
OCEANVIEW
$1,535
BALCONY
$2,159
SUITE
$2,515
From 1,297
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
15 Day Treasures Of The Pacific Coast - Panama To Chile with Hurtigruten
Cruise

15 Days (14 Nights) Colon to Valparaiso
Cruise Line: Hurtigruten
Ships: MS Fram, MS Roald Amundsen
Departures: Oct 2024 to Oct 2024
Countries Visited: Panama, Ecuador, Peru, Chile
Exclusive Deal
INSIDE
$11,486
OCEANVIEW
$6,549
BALCONY
-
SUITE
$9,145
Save 3,984
From 6,549
View Trip
6 Day Galapagos at a Glance: Southern Islands (Grand Daphne) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Short Break, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,548
From 3,820
View Trip
15 Day Chilean Fjords – Discovering The Heart Of Patagonia with Hurtigruten
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Hurtigruten
Ship: MS Fridtjof Nansen
Departure: 17 October 2025
Countries Visited: Chile, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
$18,046
BALCONY
$21,097
SUITE
$24,788
Save 5,586
From 18,046
View Trip
6 Day Galapagos Encounter: Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Short Break, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,557
From 3,693
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 29 December 2024
Countries Visited: Uruguay, Brazil, Argentina
Early Booking Offer
INSIDE
$2,696
OCEANVIEW
-
BALCONY
$3,389
SUITE
-
From 2,696
View Trip
10 Day Galapagos - Central, North, South & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 226
From 10,751
View Trip
12 Day Valparaiso to Puerto Williams with Silversea
Cruise

12 Days (11 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 12 October 2025
Countries Visited: Chile, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$20,394
From 20,394
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador
Exclusive Savings
From 19,560
View Trip
33 Day Cape Horn & Strait of Magellan Grand Adventure with Princess
Cruise

33 Days (32 Nights) Buenos Aires to Los Angeles
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 07 March 2025
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Costa Rica, Mexico, USA
INSIDE
$4,888
OCEANVIEW
$5,235
BALCONY
$8,749
SUITE
$10,135
From 4,888
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,188
From 6,103
View Trip
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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Manaus Marseille Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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