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Cruises from Miami to Panama City

Are you looking for a cruise from Miami to Panama City? December is the most popular month to cruise between Miami and Panama City and there are 9 departures available from four of the world's leading cruise lines.
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9 Cruises (9 Cruise Departures)
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 23 March 2025
Countries Visited: USA, Mexico, Guatemala, Belize (+3 more), Honduras, Costa Rica, Panama
Exclusive Deal
INSIDE
$5,138
OCEANVIEW
$5,514
BALCONY
$7,732
SUITE
$10,266
Save 2,032
From 5,138
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 08 February 2025
Countries Visited: USA, Mexico, Belize, Guatemala (+3 more), Honduras, Costa Rica, Panama
Exclusive Deal
INSIDE
$5,465
OCEANVIEW
$5,999
BALCONY
$8,207
SUITE
$10,741
Save 2,035
From 5,465
View Trip
13 Day Majestic Beaches & Canal Crossing with Regent Seven Seas
Cruise

13 Days (12 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 03 January 2026
Countries Visited: USA, Cayman Islands, Jamaica, Bonaire (+5 more), Curacao, Aruba, Colombia, Costa Rica, Panama
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,690
SUITE
$12,363
Save 5,850
From 11,690
View Trip
16 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 04 January 2025
Countries Visited: USA, Dominican Republic, Puerto Rico, Virgin Islands (+7 more), Saint Lucia, Trinidad and Tobago, Grenada, Aruba, Colombia, Panama, Costa Rica
Free At Sea OfferExclusive Solo Offer
INSIDE
$3,578
OCEANVIEW
$4,079
BALCONY
$5,886
SUITE
$6,311
From 3,578
View Trip
11 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 12 December 2025
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
Free At Sea OfferExclusive Solo Offer
INSIDE
$3,087
OCEANVIEW
$3,543
BALCONY
$4,757
SUITE
$5,137
From 3,087
View Trip
10 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Miami to Panama City
Ship: Norwegian Gem
Departure: 02 December 2024
Countries Visited: USA, Dominican Republic, Curacao, Aruba (+1 more), Panama
Free At Sea OfferExclusive Solo Offer
INSIDE
$2,438
OCEANVIEW
$2,666
BALCONY
$3,835
SUITE
$3,986
From 2,438
View Trip
11 Day Vivid Western Caribbean with Oceania Cruises
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 April 2026
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
Exclusive Deal
INSIDE
$5,028
OCEANVIEW
$5,483
BALCONY
$7,928
SUITE
$10,928
Save 2,032
From 5,028
View Trip
10 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 01 November 2025
Countries Visited: USA, Dominican Republic, Aruba, Colombia (+1 more), Panama
Free At Sea OfferExclusive Solo Offer
INSIDE
$2,735
OCEANVIEW
$3,191
BALCONY
$4,329
SUITE
$4,632
From 2,735
View Trip
11 Day Panama Canal Voyage with Azamara Cruises
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 03 December 2024
Countries Visited: USA, Aruba, Bonaire, Curacao (+2 more), Colombia, Panama
INSIDE
$3,983
OCEANVIEW
$4,345
BALCONY
$5,206
SUITE
$7,506
From 3,983
View Trip
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Cruises from Miami to Panama City

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