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All Panama Tours & Cruises

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181 Days
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231 Trips (570 Trip Departures)
21 Day Andes & South America with Princess
Cruise

21 Days (20 Nights) Los Angeles to Santiago
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 16 November 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+3 more), Ecuador, Peru, Chile
INSIDE
$4,488
OCEANVIEW
$4,528
BALCONY
$5,835
SUITE
$7,340
From 4,488
View Trip
11 Day Panama Canal - Tampa with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Tampa to Panama City
Ship: Norwegian Jade
Departure: 16 January 2026
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
INSIDE
$2,624
OCEANVIEW
$3,083
BALCONY
$4,306
SUITE
$4,688
From 2,624
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ships: Caribbean Princess, Emerald Princess
Departures: Oct 2024 to Mar 2026
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
INSIDE
$1,747
OCEANVIEW
$1,885
BALCONY
$2,975
SUITE
$3,599
From 1,747
View Trip
12 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Ship: Norwegian Pearl
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Jamaica, Colombia, Panama (+3 more), Costa Rica, Belize, Mexico
Exclusive Solo Offer
INSIDE
$2,938
OCEANVIEW
$3,687
BALCONY
$5,384
SUITE
$5,689
From 2,938
View Trip
22 Day Panama Canal & Pacific Coast with Princess
Cruise

22 Days (21 Nights) Orlando to Vancouver
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 14 April 2025
Countries Visited: USA, Bahamas, Colombia, Panama (+3 more), Costa Rica, Mexico, Canada
INSIDE
$3,163
OCEANVIEW
$3,413
BALCONY
$4,726
SUITE
$6,737
From 3,163
View Trip
21 Day Panama Canal - Ocean to Ocean with Princess
Cruise

21 Days (20 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 24 September 2024
Countries Visited: Canada, USA, Mexico, Guatemala (+3 more), Costa Rica, Panama, Colombia
INSIDE
$3,294
OCEANVIEW
-
BALCONY
-
SUITE
$7,373
From 3,294
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Emerald Princess
Departure: 30 December 2024
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
INSIDE
$2,082
OCEANVIEW
$2,250
BALCONY
$3,231
SUITE
$4,468
From 2,082
View Trip
17 Day Panama Canal Westward Cruise with Celebrity Cruises
Cruise

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 17 April 2025
Countries Visited: USA, Cayman Islands, Colombia, Panama (+3 more), Costa Rica, Guatemala, Mexico
Exclusive Deal
INSIDE
$3,257
OCEANVIEW
$3,776
BALCONY
$5,622
SUITE
$26,836
Save 4,751
From 3,257
View Trip
11 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 12 December 2025
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
INSIDE
$2,683
OCEANVIEW
$3,142
BALCONY
$4,365
SUITE
$4,748
From 2,683
View Trip
26 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

26 Days (25 Nights) Tampa to Whittier
Ship: Norwegian Jade
Departure: 03 April 2025
Countries Visited: USA, Colombia, Panama, Costa Rica (+3 more), Nicaragua, Guatemala, Mexico
INSIDE
$5,301
OCEANVIEW
$5,990
BALCONY
$8,742
SUITE
$10,501
From 5,301
View Trip
22 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

22 Days (21 Nights) Seattle to Miami
Ship: Norwegian Joy
Departure: 29 September 2025
Countries Visited: USA, Canada, Mexico, Guatemala (+3 more), Costa Rica, Panama, Colombia
INSIDE
$4,831
OCEANVIEW
$5,902
BALCONY
$6,513
SUITE
$7,508
From 4,831
View Trip
17 Day Panama Canal Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) Los Angeles to Tampa
Cruise Line: Royal Caribbean
Ship: Radiance of the Seas
Departure: 05 October 2024
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+3 more), Panama, Colombia, Cayman Islands
Exclusive Deal
INSIDE
$5,832
OCEANVIEW
-
BALCONY
$8,731
SUITE
-
Save 3,667
From 5,832
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 17 November 2025
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
INSIDE
$2,098
OCEANVIEW
$2,149
BALCONY
$3,246
SUITE
$4,177
From 2,098
View Trip
33 Day Fort Lauderdale to Buenos Aires with Silversea
Cruise

33 Days (32 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 20 January 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+3 more), Peru, Chile, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$26,532
From 26,532
View Trip
11 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Galveston to Panama City
Ship: Norwegian Jade
Departure: 06 February 2026
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
INSIDE
$2,696
OCEANVIEW
$3,109
BALCONY
$4,409
SUITE
$4,837
From 2,696
View Trip
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) Miami to Seattle
Ship: Norwegian Encore
Departure: 11 April 2026
Countries Visited: USA, Colombia, Panama, Costa Rica (+3 more), Guatemala, Mexico, Canada
INSIDE
$5,299
OCEANVIEW
$6,644
BALCONY
$8,128
SUITE
$9,183
From 5,299
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 09 February 2026
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
INSIDE
$2,530
OCEANVIEW
$2,611
BALCONY
$3,916
SUITE
$4,688
From 2,530
View Trip
10 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Miami
Ship: Norwegian Gem
Departure: 11 December 2024
Countries Visited: Panama, Costa Rica, Jamaica, Cayman Islands (+3 more), Mexico, Bahamas, USA
INSIDE
$1,988
OCEANVIEW
$2,263
BALCONY
$3,332
SUITE
$3,516
From 1,988
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departures: Nov 2025 to Feb 2026
Countries Visited: USA, Cayman Islands, Jamaica, Costa Rica (+3 more), Panama, Aruba, Curacao
INSIDE
$2,091
OCEANVIEW
$2,139
BALCONY
$3,239
SUITE
$4,160
From 2,091
View Trip
22 Day Panama Canal - Tampa with Norwegian Cruise Line
Cruise

22 Days (21 Nights) Miami to Seattle
Ship: Norwegian Encore
Departure: 30 March 2025
Countries Visited: USA, Colombia, Panama, Costa Rica (+3 more), Guatemala, Mexico, Canada
INSIDE
$4,050
OCEANVIEW
$5,197
BALCONY
$6,115
SUITE
$6,726
From 4,050
View Trip
22 Day Panama Canal - Tampa with Norwegian Cruise Line
Cruise

22 Days (21 Nights) Seattle to Miami
Ship: Norwegian Encore
Departure: 13 October 2024
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+3 more), Panama, Colombia, Cayman Islands
Exclusive Solo Offer
INSIDE
$4,252
OCEANVIEW
$4,558
BALCONY
$5,491
SUITE
$5,919
From 4,252
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ships: Caribbean Princess, Emerald Princess
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Aruba, Bonaire, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
INSIDE
$2,083
OCEANVIEW
$2,132
BALCONY
$3,231
SUITE
$4,152
From 2,083
View Trip
44 Day Best of Central America with Intrepid Travel
Tour
 (1)

44 Days Playa del Carmen to Panama City
Operated By: Intrepid Travel
Departures: Jun 2024 to Nov 2025
Trip Styles: Adventure, Small Group
Countries Visited: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Limited Time Sale
Save 758
From 6,192
View Trip
18 Day West Indies & Panama Canal Passage with Viking Cruises
New ReleaseCruise
 (4)

18 Days (17 Nights) San Juan to Los Angeles
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 31 March 2025
Countries Visited: Puerto Rico, Curacao, Colombia, Panama (+4 more), Costa Rica, Nicaragua, Mexico, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$10,885
SUITE
$20,785
Save 1,110
From 10,885
View Trip
18 Day West Indies & Panama Canal Passage with Viking Cruises
New ReleaseCruise
 (4)

18 Days (17 Nights) Los Angeles to San Juan
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 02 October 2025
Countries Visited: USA, Mexico, Nicaragua, Costa Rica (+4 more), Panama, Colombia, Curacao, Puerto Rico
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$19,795
Save 1,100
From 9,895
View Trip
34 Day Andes & Cape Horn Grand Adventure with Princess
Cruise
 (3)

34 Days (33 Nights) Los Angeles to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departure: 01 December 2024
Countries Visited: USA, Mexico, Panama, Peru (+4 more), Chile, Argentina, Falkland Islands, Uruguay
INSIDE
$5,281
OCEANVIEW
-
BALCONY
$7,727
SUITE
$9,875
From 5,281
View Trip
11 Day Western Caribbean Bliss with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Cartagena
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 03 December 2024
Countries Visited: USA, Mexico, Belize, Guatemala (+4 more), Honduras, Costa Rica, Panama, Colombia
Cabin Upgrade Offer
INSIDE
$3,420
OCEANVIEW
$3,420
BALCONY
$4,113
SUITE
$5,717
From 3,420
View Trip
12 Day Classic Panama Canal with Oceania Cruises
Cruise
 (2)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Bonaire, Jamaica, Bahamas, USA
Exclusive Deal
INSIDE
$5,931
OCEANVIEW
$6,386
BALCONY
$8,831
SUITE
$17,335
Save 2,039
From 5,931
View Trip
23 Day Panama Canal with Holland America
Cruise
 (2)

23 Days (22 Nights) Fort Lauderdale to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 10 April 2026
Countries Visited: USA, Colombia, Panama, Costa Rica (+4 more), El Salvador, Guatemala, Mexico, Canada
Have It All Offer
INSIDE
$6,505
OCEANVIEW
$7,693
BALCONY
$8,287
SUITE
$10,069
From 6,505
View Trip
45 Day Epic Central America with Intrepid Travel
Tour

45 Days Mexico City to San Jose
Operated By: Intrepid Travel
Departures: Aug 2024 to Nov 2024
Trip Styles: Adventure, Small Group, 18-30's
Countries Visited: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
Save 124
From 5,708
View Trip
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