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All Central America Cruises

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235 Cruises (536 Cruise Departures)
23 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

23 Days (22 Nights) Miami to Seattle
Ship: Norwegian Encore
Departure: 11 April 2026
Countries Visited: USA, Colombia, Panama, Costa Rica (+3 more), Guatemala, Mexico, Canada
INSIDE
$5,299
OCEANVIEW
$6,644
BALCONY
$8,128
SUITE
$9,183
From 5,299
View Trip
21 Day Panama Canal Connoisseur with Oceania Cruises
Cruise

21 Days (20 Nights) Tampa to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 25 March 2026
Countries Visited: USA, Mexico, Belize, Honduras (+7 more), Costa Rica, Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands
Exclusive Deal
INSIDE
$8,894
OCEANVIEW
$9,804
BALCONY
$14,388
SUITE
$20,071
Save 2,056
From 8,894
View Trip
21 Day Panama Canal with Holland America
Cruise

21 Days (20 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 05 April 2026
Countries Visited: USA, Colombia, Costa Rica, El Salvador (+3 more), Guatemala, Mexico, Canada
Have It All Offer
INSIDE
$6,553
OCEANVIEW
$7,345
BALCONY
$8,830
SUITE
$12,097
From 6,553
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 09 February 2026
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
Exclusive Deal
INSIDE
$2,522
OCEANVIEW
$2,603
BALCONY
$3,908
SUITE
$4,680
From 2,522
View Trip
13 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Miami to Lima
Ship: Norwegian Jade
Departure: 27 February 2026
Countries Visited: USA, Colombia, Panama, Ecuador (+1 more), Peru
INSIDE
$3,763
OCEANVIEW
$3,947
BALCONY
$6,013
SUITE
$6,212
From 3,763
View Trip
32 Day Circle Hawaii & Panama Canal Holiday with Holland America
Cruise
 (1)

32 Days (31 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2024
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Colombia, Bahamas
Have It All Offer
INSIDE
$8,009
OCEANVIEW
$8,534
BALCONY
$14,860
SUITE
-
From 8,009
View Trip
34 Day Seattle To Miami with Cunard
Cruise
 (9)

34 Days (33 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+8 more), Colombia, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Sint Maarten, Virgin Islands
Exclusive Deal
INSIDE
$5,208
OCEANVIEW
$6,149
BALCONY
$7,287
SUITE
$18,623
From 5,208
View Trip
29 Day Seattle To Miami with Cunard
Cruise
 (9)

29 Days (28 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 18 September 2025
Countries Visited: USA, Canada, Mexico, Costa Rica (+3 more), Panama, Colombia, Aruba
Exclusive Deal
INSIDE
$4,711
OCEANVIEW
$5,602
BALCONY
$6,741
SUITE
$17,334
From 4,711
View Trip
32 Day South America, Inca & Panama Canal Discovery with Holland America
Cruise
 (1)

32 Days (31 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Panama, Cayman Islands, USA
Have It All Offer
INSIDE
$7,988
OCEANVIEW
$8,255
BALCONY
$10,532
SUITE
$14,096
From 7,988
View Trip
19 Day Andes & South America with Princess
Cruise
 (3)

19 Days (18 Nights) Los Angeles to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departure: 01 December 2024
Countries Visited: USA, Mexico, Panama, Peru (+1 more), Chile
Exclusive Deal
INSIDE
$2,330
OCEANVIEW
-
BALCONY
$3,053
SUITE
$3,884
From 2,330
View Trip
16 Day Central America Tapestry Voyage with Azamara Cruises
Cruise
 (1)

16 Days (15 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 January 2026
Countries Visited: USA, Mexico, Costa Rica, Panama (+2 more), Ecuador, Peru
INSIDE
$5,382
OCEANVIEW
$6,333
BALCONY
$8,056
SUITE
$11,506
From 5,382
View Trip
21 Day Andes & South America with Princess
Cruise

21 Days (20 Nights) Los Angeles to Santiago
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 16 November 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+3 more), Ecuador, Peru, Chile
Exclusive Deal
INSIDE
$3,193
OCEANVIEW
$3,292
BALCONY
$4,539
SUITE
$6,044
From 3,193
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2024 to Oct 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+2 more), Peru, Chile
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$14,845
SUITE
$20,785
Save 1,150
From 14,845
View Trip
18 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

18 Days (17 Nights) Lima to San Diego
Ship: Norwegian Jade
Departure: 11 March 2026
Countries Visited: Peru, Ecuador, Panama, Costa Rica (+5 more), Nicaragua, El Salvador, Guatemala, Mexico, USA
INSIDE
$4,198
OCEANVIEW
$4,840
BALCONY
$7,333
SUITE
$8,021
From 4,198
View Trip
42 Day New York To Sydney with Cunard
Cruise

42 Days (41 Nights) New York to Sydney
Cruise Line: Cunard
Ship: Queen Anne
Departure: 18 January 2025
Countries Visited: USA, Aruba, Panama, Guatemala (+5 more), Mexico, Samoa, Tonga, New Zealand, Australia
Exclusive Deal
INSIDE
$11,200
OCEANVIEW
-
BALCONY
$18,328
SUITE
$33,129
From 11,200
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2025 to Mar 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Mexico, USA
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$15,340
SUITE
$22,765
Save 1,160
From 15,340
View Trip
37 Day Andes & Cape Horn Grand Adventure with Princess
Cruise

37 Days (36 Nights) Los Angeles to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 16 November 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+6 more), Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$7,098
OCEANVIEW
$7,019
BALCONY
$10,316
SUITE
$13,157
From 7,019
View Trip
23 Day Palms To Andean Peaks with Oceania Cruises
Cruise

23 Days (22 Nights) Miami to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 29 November 2025
Countries Visited: USA, Mexico, Belize, Guatemala (+6 more), Honduras, Costa Rica, Panama, Ecuador, Peru, Chile
Exclusive Deal
INSIDE
$9,556
OCEANVIEW
$11,080
BALCONY
$12,615
SUITE
$18,466
Save 2,064
From 9,556
View Trip
61 Day Circle South America with Oceania Cruises
Cruise

61 Days (60 Nights) Miami to San Diego
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 06 January 2026
Countries Visited: USA, Saint Barthelemy, Dominica, Barbados (+12 more), French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Chile, Peru, Ecuador, Costa Rica, Nicaragua, El Salvador, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$32,238
SUITE
$50,939
Save 2,252
From 32,238
View Trip
39 Day World Cruise Segment - New York to Sydney with Princess
Cruise

39 Days (38 Nights) New York to Sydney
Cruise Line: Princess
Ship: Crown Princess
Departure: 26 July 2026
Countries Visited: USA, Colombia, Ecuador, Peru (+5 more), Easter Island, Pitcairn Islands, French Polynesia, New Zealand, Australia
Exclusive Deal
INSIDE
$11,098
OCEANVIEW
$11,435
BALCONY
$15,207
SUITE
$20,632
From 11,098
View Trip
27 Day Southampton To San Francisco with Cunard
Cruise

27 Days (26 Nights) London to San Francisco
Cruise Line: Cunard
Ship: Queen Anne
Departure: 09 January 2025
Countries Visited: England, USA, Aruba, Panama (+2 more), Guatemala, Mexico
Exclusive Deal
INSIDE
$6,938
OCEANVIEW
$9,859
BALCONY
$10,898
SUITE
$19,808
From 6,938
View Trip
18 Day Panama Canal with Holland America
Cruise
 (2)

18 Days (17 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Koningsdam
Departure: 01 November 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Aruba, Bahamas
Have It All Offer
INSIDE
$5,139
OCEANVIEW
$6,327
BALCONY
$6,723
SUITE
$8,703
From 5,139
View Trip
16 Day Caribbean & Panama Canal with Viking Cruises
Cruise
 (5)

16 Days (15 Nights) San Juan to Los Angeles
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 29 March 2026
Countries Visited: Puerto Rico, Curacao, Colombia, Panama (+3 more), Costa Rica, Mexico, USA
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,410
SUITE
$16,825
Save 1,085
From 8,410
View Trip
21 Day Panoramic Panama Canal with Oceania Cruises
Cruise

21 Days (20 Nights) San Diego to New York
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 July 2025
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Colombia, Cayman Islands
Cabin Upgrade Offer
INSIDE
$8,828
OCEANVIEW
$8,828
BALCONY
$10,046
SUITE
$19,698
From 8,828
View Trip
32 Day Western Caribbean Explorer & Panama Canal with Holland America
Cruise

32 Days (31 Nights) Fort Lauderdale to Seattle
Cruise Line: Holland America
Ship: Eurodam
Departure: 02 April 2025
Countries Visited: USA, Bahamas, Jamaica, Honduras (+6 more), Belize, Mexico, Colombia, Costa Rica, Guatemala, Canada
Have It All Offer
INSIDE
$8,713
OCEANVIEW
$9,525
BALCONY
$11,109
SUITE
$17,069
From 8,713
View Trip
17 Day Panama Canal Adventure with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 08 January 2025
Countries Visited: USA, Cayman Islands, Colombia, Costa Rica (+3 more), Nicaragua, Guatemala, Mexico
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,763
SUITE
-
Save 2,097
From 11,763
View Trip
18 Day Panama Canal with Holland America
Cruise

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 13 April 2025
Countries Visited: USA, Turks and Caicos Islands, Aruba, Colombia (+3 more), Costa Rica, El Salvador, Mexico
Have It All Offer
INSIDE
$5,206
OCEANVIEW
$5,761
BALCONY
$6,454
SUITE
$10,612
From 5,206
View Trip
35 Day Caribbean Gems & Panama Canal with Seabourn
Cruise

35 Days (34 Nights) Miami to Los Angeles
Cruise Line: Seabourn
Ship: Sojourn
Departure: 13 November 2025
Countries Visited: USA, Puerto Rico, Saint Barthelemy, Guadeloupe (+9 more), Dominica, Saint Kitts and Nevis, Virgin Islands, Dominican Republic, Curacao, Colombia, Costa Rica, Guatemala, Mexico
The Sail Away Event
INSIDE
-
OCEANVIEW
$19,989
BALCONY
$24,112
SUITE
-
From 19,989
View Trip
18 Day Panama Canal with Holland America
Cruise

18 Days (17 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departure: 09 October 2025
Countries Visited: USA, Mexico, Guatemala, El Salvador (+2 more), Costa Rica, Aruba
Have It All Offer
INSIDE
$5,336
OCEANVIEW
$6,128
BALCONY
$7,613
SUITE
$11,276
From 5,336
View Trip
25 Day Western Caribbean Explorer & Panama Canal with Holland America
Cruise

25 Days (24 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 02 April 2025
Countries Visited: USA, Bahamas, Jamaica, Honduras (+5 more), Belize, Mexico, Colombia, Costa Rica, Guatemala
Have It All Offer
INSIDE
$7,385
OCEANVIEW
$8,187
BALCONY
$9,771
SUITE
$15,731
From 7,385
View Trip
Results: 151-180 of 235

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South & Central America Cruises

Amazon Cruises Bahamas Cruises Belize Cruises Bermunda Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Colombia Cruises Costa Rica Cruises Ecuador Cruises Falkland Island Cruises Galapagos Cruises Honduras Cruises Mexico Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises South America Cruises USA Cruises

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Country Routes

Cruises from Peru to Argentina Cruises from Puerto Rico to USA Cruises from England to Canada Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from French Polynesia to New Zealand Cruises from Argentina to Chile Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Spain Cruises from England to USA Cruises from French Polynesia to USA Cruises from New Zealand to Australia Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Singapore to Australia Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to England Cruises from USA to French Polynesia Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

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