Home > All River Cruises > Asia River Cruises > Mekong River Cruises > Vietnam > October 2025

Vietnam River Cruises Starting In October 2025

If you're looking at joining a river cruise through Vietnam in October 2025, we have 40 unique river cruise itineraries and 725 departures available, operated by seven of the world's leading river cruise lines departing in October.
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Departures (October 2025)
< September 2025 November 2025 >
Duration
8 Days
25 Days
Countries Visited
Start & End Cities
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Price
$2,700pp
$34,080pp
Countries
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40 River Cruises (725 River Cruise Departures)
13 Day Vietnam and Cambodia Highlights with APT
River Cruise
 (2)

13 Days Siem Reap to Ho Chi Minh City
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
Save 3,558
From 6,834
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13 Day Vietnam and Cambodia Highlights with APT
River Cruise
 (7)

13 Days Ho Chi Minh City to Siem Reap
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 3,558
From 6,834
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8 Day Mekong Discovery with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive DealEarlybird Offer
Save 2,852
From 4,494
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21 Day Best of Vietnam and Cambodia with APT
River Cruise
 (5)

21 Days Hanoi to Siem Reap
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 4,095
From 10,796
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21 Day Best of Vietnam and Cambodia with APT
River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 4,101
From 11,192
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17 Day Vietnam and Cambodia Discovery with APT
River Cruise
 (3)

17 Days Hanoi to Siem Reap
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 4,077
From 9,112
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25 Day Vietnam and Cambodia Grand Tour with APT
River Cruise
 (3)

25 Days Hanoi to Siem Reap
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Mar 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 4,119
From 13,074
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8 Day Mekong Discovery with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,849
From 4,494
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15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Ships: Mekong Jewel
Departures: Sep 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Earlybird SavingExclusive Deal
Save 1,613
From 10,783
View Trip
17 Day Vietnam and Cambodia Discovery with APT
River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 4,080
From 9,409
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16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,886
From 8,694
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21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

21 Days Hanoi to Siem Reap
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$7,618
BALCONY
$8,405
SUITE
$11,276
Save 1,605
From 7,618
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8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

8 Days Ho Chi Minh City to Phnom Penh
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,000
BALCONY
$4,787
SUITE
$7,658
Save 568
From 4,000
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13 Day Treasures of the Mekong with Scenic
River Cruise
 (1)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Nov 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,920
SUITE
$10,588
Save 2,404
From 7,920
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13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Ho Chi Minh City to Siem Reap
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: May 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,945
BALCONY
$5,732
SUITE
$8,603
Save 1,578
From 4,945
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13 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,945
BALCONY
$5,732
SUITE
$8,603
Save 2,055
From 4,945
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

17 Days Hanoi to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$6,777
BALCONY
$7,564
SUITE
$10,435
Save 1,586
From 6,777
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

8 Days Phnom Penh to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,000
BALCONY
$4,787
SUITE
$7,658
Save 558
From 4,000
View Trip
10 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Phnom Penh to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2024 to Oct 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,495
BALCONY
$5,282
SUITE
$7,163
Save 555
From 4,495
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

21 Days Hanoi to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$8,212
BALCONY
$8,999
SUITE
$11,276
Save 1,595
From 8,212
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,871
From 6,842
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Ships: Mekong Jewel
Departures: Sep 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Earlybird SavingExclusive Deal
Save 1,596
From 10,783
View Trip
18 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Mar 2025 to Oct 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$12,717
SUITE
$15,385
Save 2,445
From 12,717
View Trip
18 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Mar 2025 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$13,113
SUITE
$15,781
Save 2,445
From 13,113
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive DealEarlybird Offer
Save 2,873
From 6,753
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Oct 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$8,509
SUITE
$11,177
Save 2,408
From 8,509
View Trip
11 Day Spiritual Cambodia and The Mekong with APT
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
Save 2,549
From 5,645
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise

15 Days Hanoi to Ho Chi Minh City
Operated By: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2024 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Discover More Sale
INSIDE
-
RIVER VIEW
-
BALCONY
$6,826
SUITE
$17,617
Save 1,552
From 6,826
View Trip
11 Day Spiritual Cambodia and The Mekong with APT
River Cruise

11 Days Siem Reap to Ho Chi Minh City
Operated By: APT
Ships: Mekong Serenity
Departures: Jul 2024 to Apr 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
Save 2,549
From 5,645
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,049
SUITE
$9,717
Save 3,502
From 7,049
View Trip
Results: 1-30 of 40

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Asia River Cruises

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Trip Lengths

3 Week

Departure Months

May 2024 July 2024 August 2024 September 2024 October 2024 November 2024 December 2024 January 2025 February 2025 March 2025 April 2025 May 2025 July 2025 August 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 August 2026 September 2026 October 2026 November 2026 December 2026

Cities

Hanoi Ho Chi Minh City

Routes

Hanoi to Ho Chi Minh City Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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