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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 448 unique cruise itineraries from 10 leading cruise lines. May and September are the most popular months to join a luxury cruise in the Mediterranean with 539 departures starting between May 2024 and April 2027.
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448 Cruises (539 Cruise Departures)
10 Day Valletta to Nice with Silversea
Cruise

10 Days (9 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 18 July 2025
Countries Visited: Malta, Sicily, Sardinia, Italy (+1 more), France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,880
BALCONY
$14,454
SUITE
$20,790
From 11,880
View Trip
6 Day Barcelona to Rome with Silversea
Cruise

6 Days (5 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 22 June 2024
Countries Visited: Spain, France, Italy
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,801
From 9,801
View Trip
11 Day Ramparts & Rivieras with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 27 August 2025
Countries Visited: Italy, Sicily, Malta, Spain (+2 more), France, Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,953
SUITE
$11,705
Save 2,067
From 7,953
View Trip
8 Day Italy Intensive Voyage with Azamara Cruises
Cruise

8 Days (7 Nights) Rome to Monte Carlo
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 29 June 2024
Countries Visited: Italy, Monaco
Circle Club Voyage
INSIDE
$1,932
OCEANVIEW
$2,110
BALCONY
-
SUITE
-
From 1,932
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 April 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,432
SUITE
-
From 24,432
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+1 more), Spain
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,197
SUITE
$6,341
From 5,197
View Trip
31 Day Malta, Morocco & Mediterranean with Seabourn
Cruise

31 Days (30 Nights) Rome to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 21 June 2025
Countries Visited: Italy, Malta, Tunisia, France (+4 more), Spain, Gibraltar, Morocco, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$23,841
SUITE
$43,028
From 23,841
View Trip
11 Day Calabrian Culture & Greek Cuisine with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 05 August 2024
Countries Visited: Spain, France, Italy, Sicily (+2 more), Montenegro, Greece
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,618
SUITE
$10,568
Save 10,312
From 9,618
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Malta, Sicily, Italy
From 18,940
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Countries Visited: Italy, Spain, France
INSIDE
$1,734
OCEANVIEW
$1,882
BALCONY
$2,328
SUITE
$4,654
From 1,734
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 July 2024
Countries Visited: Italy, France, Spain, Sardinia (+2 more), Corsica, Sicily
INSIDE
-
OCEANVIEW
$3,192
BALCONY
$3,677
SUITE
$8,320
From 3,192
View Trip
11 Day Mediterranean Wanderlust with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 September 2025
Countries Visited: Spain, France, Italy, Malta (+1 more), Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,465
SUITE
$15,010
Save 6,175
From 13,465
View Trip
8 Day Balkan Jewels with Seabourn
Cruise

8 Days (7 Nights) Dubrovnik to Athens
Cruise Line: Seabourn
Ship: Encore
Departures: Jun 2024 to Sep 2025
Countries Visited: Croatia, Montenegro, Italy, Albania (+1 more), Greece
The Sail Away EventMore Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,143
SUITE
$10,104
From 6,143
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, Corsica, Sicily, Italy
INSIDE
$1,387
OCEANVIEW
$1,585
BALCONY
$1,783
SUITE
$3,763
From 1,387
View Trip
8 Day Riviera Gems & The Calanques with Seabourn
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 08 April 2025
Countries Visited: Monaco, Italy, Sardinia, France (+1 more), Spain
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,422
SUITE
$11,030
From 8,422
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
8 Day Mediterranean Tapestry with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 15 November 2024
Countries Visited: Italy, France, Spain
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$3,830
BALCONY
$5,006
SUITE
$5,927
Save 7,440
From 3,830
View Trip
17 Day Civitavecchia to Barcelona with Silversea
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 22 July 2025
Countries Visited: Italy, Sicily, Monaco, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,513
From 18,513
View Trip
6 Day Grand Prix Weekend Voyage with Azamara Cruises
Cruise

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 23 May 2024
Countries Visited: Spain, France
INSIDE
-
OCEANVIEW
-
BALCONY
$4,824
SUITE
-
From 4,824
View Trip
11 Day Riviera & Mediterranean Jewels with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Jul 2024 to Nov 2025
Countries Visited: Italy, Malta, Tunisia, France (+1 more), Spain
The Sail Away EventMore Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,424
SUITE
$15,913
From 8,424
View Trip
17 Day Discover Malta, Italy & France with Emerald Cruises
New ReleaseCruise

17 Days (16 Nights) Valletta to Nice
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 05 May 2026
Countries Visited: Malta, Sicily, Italy, Corsica (+2 more), Monaco, France
Exclusive Deal
INSIDE
-
OCEANVIEW
$16,672
BALCONY
-
SUITE
$22,810
Save 5,168
From 16,672
View Trip
11 Day Spain & Moroccan Gems with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, France, Gibraltar, Morocco
The Sail Away EventMore Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,676
SUITE
$15,913
From 8,676
View Trip
10 Day Forums & Frescoes with Oceania Cruises
Cruise

10 Days (9 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 11 November 2024
Countries Visited: Greece, Montenegro, Croatia, Malta (+2 more), Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,842
SUITE
$9,129
Save 2,048
From 5,842
View Trip
15 Day Western Mediterranean with Cunard
Cruise

15 Days (14 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 28 July 2024
Countries Visited: England, Spain, Italy, Gibraltar
INSIDE
$3,568
OCEANVIEW
$4,360
BALCONY
$5,548
SUITE
$11,290
From 3,568
View Trip
9 Day A Journey To Elegant Enclaves On Old European Shores with Explora Journeys
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 11 August 2024
Countries Visited: Spain, France, Italy
Unique EscapesExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,331
SUITE
$10,182
From 8,331
View Trip
8 Day Azure Summer with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 May 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,034
SUITE
$9,766
Save 5,826
From 9,034
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jul 2026 to Sep 2026
Countries Visited: Italy, France
INSIDE
$1,635
OCEANVIEW
$1,783
BALCONY
$1,932
SUITE
$4,258
From 1,635
View Trip
12 Day Barcelona to Rome with Silversea
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 26 April 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,553
From 14,553
View Trip
11 Day A Journey From Athens To Barcelona with Explora Journeys
Cruise

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 October 2024
Countries Visited: Greece, Malta, Italy, France (+1 more), Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$5,881
SUITE
$7,187
From 5,881
View Trip
8 Day French & Italian Rivieras plus Monaco Grand Prix Option with Scenic
Cruise

8 Days (7 Nights) Nice to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 20 May 2025
Countries Visited: France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,994
SUITE
$14,711
Save 2,101
From 9,994
View Trip
Results: 91-120 of 448

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