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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 115 unique cruise itineraries from 8 leading cruise lines. March is the most popular month to join a luxury cruise around South America with 240 departures starting between June 2024 and March 2026.
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86 Days
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115 Cruises (240 Cruise Departures)
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
INSIDE
$5,330
OCEANVIEW
$6,365
BALCONY
$7,515
SUITE
$8,780
From 5,330
View Trip
11 Day Peru & Chile Voyage with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Lima to San Antonio
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 23 January 2025
Countries Visited: Peru, Chile
Circle Club Voyage
INSIDE
$4,689
OCEANVIEW
$5,408
BALCONY
$6,271
SUITE
$9,720
From 4,689
View Trip
26 Day Carnival Rio & Amazon Voyage with Azamara Cruises
Cruise
 (1)

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+1 more), Barbados
Circle Club Voyage
INSIDE
$9,243
OCEANVIEW
$11,052
BALCONY
-
SUITE
-
From 9,243
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$18,569
SUITE
$28,614
Save 327
From 17,393
View Trip
10 Day Ocean Voyage: Hanga Roa - Ushuaia with Ponant
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save 54
From 3,296
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 05 April 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$21,087
SUITE
$40,788
From 21,087
View Trip
22 Day The Complete Amazon Experience & Coast Of Brazil with Seabourn
Cruise

22 Days (21 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,065
SUITE
$41,821
From 24,065
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
$11,801
OCEANVIEW
$13,405
BALCONY
$15,009
SUITE
$21,493
Save 2,089
From 11,801
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$22,473
BALCONY
$25,641
SUITE
$38,709
From 22,473
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departure: 21 March 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$37,323
From 20,592
View Trip
13 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

13 Days (12 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 30 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$12,402
SUITE
$17,115
From 12,402
View Trip
13 Day Bounty Of Brazil with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 January 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$6,185
OCEANVIEW
$6,947
BALCONY
$7,709
SUITE
$10,719
Save 2,045
From 6,185
View Trip
13 Day Valparaiso to Puerto Williams with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 07 November 2024
Countries Visited: Argentina, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,593
BALCONY
$12,276
SUITE
$19,800
From 10,593
View Trip
23 Day Beauty At The End Of The World with Regent Seven Seas
Cruise

23 Days (22 Nights) Rio de Janeiro to Santiago
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 25 January 2025
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,501
SUITE
$16,980
Save 17,549
From 15,501
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,420
SUITE
$8,955
Save 2,050
From 6,420
View Trip
13 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 22 March 2025
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,449
SUITE
$18,706
Save 5,646
From 14,449
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Wind
Departure: 10 November 2024
Countries Visited: Peru, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,326
BALCONY
$8,712
SUITE
-
From 7,326
View Trip
12 Day Crossing the Equator: Barbados to Brazil with Scenic
Cruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 November 2024
Countries Visited: Brazil, French Guiana, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,960
SUITE
$10,207
Save 10,570
From 6,960
View Trip
13 Day Valparaiso to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 February 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,117
From 13,117
View Trip
11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,124
OCEANVIEW
$5,807
BALCONY
$6,421
SUITE
$8,955
Save 2,036
From 5,124
View Trip
19 Day Around Cape Horn with Oceania Cruises
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 03 February 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+1 more), Peru
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,182
SUITE
$16,152
Save 2,078
From 10,182
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$9,405
BALCONY
$11,385
SUITE
-
From 9,405
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,672
From 7,672
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departures: Nov 2024 to Oct 2025
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,623
SUITE
$14,365
Save 7,607
From 10,623
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$18,357
SUITE
$34,851
From 18,357
View Trip
13 Day Beautiful Brazil & Beyond with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 24 March 2025
Countries Visited: Argentina, Uruguay, Brazil
Cabin Upgrade Offer
INSIDE
$5,987
OCEANVIEW
$6,898
BALCONY
$6,898
SUITE
$8,274
From 5,987
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Jun 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 24,330
View Trip
Results: 1-30 of 115

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